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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4866373625961ceaa476fe87c04b456c2bbf28436adb7e172a467b5bf24abffa' 
  AND token = '8BtHq6oB2f3l3VmvzF+K8sDxK8D6qZfoVz33TRdZRFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}