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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86f166608e41a39e5d567d90cc504e4155a345a98c4d0b992816338e290ea2a' 
  AND token = 'vM3klncPQ+enI5IegeMTNLfEd0lfhE/64c8lguZVClM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}