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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14158906a6f91885a4a5906c13f7100863d1db12d570f531f0204b2e4dcd468a' 
  AND token = 'P4Z0KEKdxB5nZInng2wvIilq30znIIEAXpvEp/VNx4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}