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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b1050b23eefcb95c87951517f3bf702ddda78380ca5c1db5f9560017e4a8e3' 
  AND token = 'B6czywqXwV+5YQlDAJBW1F2wbkytTmB487hNtgs1ZE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}