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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943e58468132b8ac5e34c84c95a22cc67c0fdd748c9b5675debdc7b2a4b182a2' 
  AND token = 'We8FQq4GY8LmUmzkKDhbCF+lE/+4RUiVFt0KVcYdLjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}