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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '588ccbec6c57e5b66ea1e5f4c1593ef3c37fe7448d181894e65cee51445ede23' 
  AND token = 'Do+ShwlLyBbtm4ass7AFxAX4fjCMKdq+50Wzl1ourPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}