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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551bbe9fb87b9b952182e195357820c858189c286ea065ca0a876cee4c4e7dfd' 
  AND token = 'Aw6FT9/GGfSY3SS0B13c1g+PjF3Hn3URAvWTXFHgMmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}