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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318c31d082869750729994f6e52abebccc1a7df6b227412057cd122b2348522b' 
  AND token = 'CsGon/UkVD48DbHvW4Nte8WoKbRcpfzRLXQlybGaicg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}