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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2f6058f8e599009d7428e39dca1466fc40464f055113a3a081d06caf46c74b' 
  AND token = 'C6hSEeA8Q33zOiFFY/gcO4EEcrqTybqHeN3iqG/lbgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}