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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca25569f5e5fd1ebf34e4e3c190bfa74ef106125b00e908bf87642353c64f6e' 
  AND token = 'tNsFRUYSnYg0PvSrPNkfozkt/3TqEGlJnw7Qtb7M6lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}