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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82e5bd2bcb5b4eaa37363bcc79044f1f0af86a36444c549f1a9cab13a07a7396' 
  AND token = '1yVRVkykR428uq5gIYpFXe+eUGw69HwonZzkRy531Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}