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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e962af6dc4f60d4aeb291d5ef3e721e56e1f2f12f9c8fa0bfbb511d70d0f08d3' 
  AND token = 'B1M+5BjPQSh21OT4DRUzCaS9AsDjakWBFFcinag+XTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}