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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef81c9b34a1e09df2b01b0e3eb3c34b218ae2803e3abae049d934ce7b3faca7b' 
  AND token = 'o+WG9+bkYFS7q/WK+ukjKOoGnhvdMD6VGHQ2Krcyp64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}