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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0e0169064baef91d3d91383006f2107401763efa3bfe686745d26a4e8212b2' 
  AND token = '1SotjaKpRQGAm0B3X3ZMD9uBt0Y8xgTCcGUrym5lWWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}