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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8808434006550edbba0258b0dc12b3c6ac9d6f7d06520d7f7dbcd613efa93f5' 
  AND token = 'NdxdNMqpk2pp9L791mY1PnHNm6gaA/frN5bFiV0ui8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}