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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d169daf3325517f1c4788e7f1240796880a010ea7fdcee1fd2d1356417d064a' 
  AND token = '2EqRZOCedriVdsWzPQ9tOmOYmHXlhjW/Un0LFKjmyco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}