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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2dd1fe97076841ba5a73d564a462a73027cc2c4d4699fd76b95ada3074c6f41' 
  AND token = 'dBMhb1lC4L67X3Tggs7dtjM8zvHnuc58jVxDnM9iBqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}