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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2143b424a7ad7ccd0ae15daab9831ac78ffa42fa672a382f0d43f520f959c1' 
  AND token = 'eSE2wj3r/auTue/k8Pvx120Ev9gmcjq+GJiPSqo/XkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}