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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63133bedb6c10f64bb63a0ed15970a18378f34a0d1b41be149c391e2e195ed38' 
  AND token = 'uOcHvye5AHx7CCgnCXN4SUZO1i/BJ0NKZmbdB7x16hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}