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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b41f153fb8095afc211eb00189db76ee70c7486da6f17766b3db39724064415' 
  AND token = 'EVmzt9pbzVjGNBsbNXaMlWnNFPHdzhm6tyq4MIXcQic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}