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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb4c8f9f5d46c1db4e4140a9db885b4251a9fbcf4cd40a77230c531b21014b9e' 
  AND token = 'cjiR21EeC+TqbRbhkt68MaeEhLDg1P26nRMaFtxj1HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}