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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed129abc4db63813fa008eab3af11a824c92a64a38ac074f3a7cd60c097f15c3' 
  AND token = 'VrZMenLqeN4RIVby5oTpNYcs2KmnWLuV1kBjF7682KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}