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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b470b54e659b62d71ef069787a1c2b14dcc419bb74986c2958c159035aab10f' 
  AND token = '5L29i/XyAzsbH82xgWm+fG5+DVzbyhQmP1EyRuXTWvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}