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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89de1064205b5300ab1b39bd521fd0717c7c5d555d0c3b9418edd48a9317d393' 
  AND token = 'u+hVlgNiR/a5vd6XQeH3bj1HRymFhkzdcOqSc0e0efE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}