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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852e0d2f012d53df94e3edb401f8f0f8c74c3dc7c02d6e22f35cb2c2a39ac2cb' 
  AND token = 'B+2GGeDi1Eu2Bdz9oWynWR14yqxYDoS7BpK4m0JivBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}