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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f583cf94e996577b9ff6ca3ae2795a72feb2734657dcddf3c52c99cf737414' 
  AND token = 'ZIkSA8WIe7e/KECssPaVHWJp7yIzPVtvpjyZE88VdX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}