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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb8a5922018b6cbed20e0153acbbb19600a10adcc7cbb28ea97f6e61d93ac8f' 
  AND token = 'DTebKpAF3WUpTcpi2U//p6tF+sTCMxz+gNo2vY+ThLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}