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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '213731e45d84a876e8fda19213edcb207dfd5cac709ab0cedde5c00fefc57cbd' 
  AND token = '4XUYKwrIMoj5s3BgD7M583aW30MiLfE55Ga1if1hbW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}