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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad934424b88146af61668dfb36f27bf2d79855f7f3bb9f9f58a1974e2462ddd4' 
  AND token = 'fdFFWaEaGw8lx0IQxct3e+pq4B8NFa0EuoBS18nWUdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}