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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28cadc60d79dd54c494bf85bfd619f8f4149d2c8594842ef760fa6cc82a9bec1' 
  AND token = 'TUX1RGCw/RgHTGe9XIynOzoN7HzRd2ZHRlWN/uXi1B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}