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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82369b833fdbfc4a0a549c5c64a6d3c5382bfd34cccb2ff403765fb7318e520b' 
  AND token = 'z+4LF3sKuEjMpnPtDGsMLzCW/49Mt6z5i+MPAFYnQew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}