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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aad7cf563637a0f7f3e19e783b1df56b996401c277b0ee6b8b69f16c85694f1' 
  AND token = 'Pg5uajZZR3obXx0KjPSzWmsKeIl/54tntsPiSCkRQQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}