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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae37320be96989e7606440595cf150d52ba62e599577bb9c8c702c7bcc640e2a' 
  AND token = 'eXzD4DhUva/dpTqWEq7uLx/MbzbzMRfm7UZjcLRFbIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}