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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eb9f57ea72ceced14c7d2bb025aab48680f7288d0e804f1bff23d34140da477' 
  AND token = 'vE/HSn61qTQsfK6jRfU/u4dWvZEGiND5YSkOS+2uIWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}