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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129cba4d342f647b7b2af48478d7906181b140111d324edfab71d4f63d89c747' 
  AND token = 'OuFnHo4A7fn2yTmm5dsza+a//LRr1eOGNoojXymCTtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}