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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c20792549c41ee6b35bb9c3bf619cb33cb9ea0e1fb146c934b481bba0b8cac4' 
  AND token = 'iTUf38qjAFb9Q1J01CemKId4Uc3PjF6zR1e+RFs955Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}