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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8fb2d0a456ba28600ac1606aecab4a5d6f4110e5a1b2b31f01ee8319efb27a' 
  AND token = 'g6BMwV6mbeQ5QZ9QzC6AyZ3A/Ht7no12UMJojhdKIrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}