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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a86864cdfde8dea7842bab7ef3b5fa8af77f9108a0a19d4f4cb2beefdd3edd2' 
  AND token = 'DDhhGDa1wsnWteomA9jRLr22miGQOUX/1Wo7saUnsqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}