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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195a9e22370a16e7c36fafb95d2e17aa9d09b183b404cd251d8b11dc090f6ab0' 
  AND token = 't5e1/h80ig5q6GJPhR5gnU5+dhoBwxmXCtDIhsmp5PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}