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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7d027e1cc2e249870b45662285fecb457a43a7053510ec5d9832e65a44f2da' 
  AND token = 'cd5/n8D45cPtqC6uPQ7f4HM7a6mgi4BhBFzSd1OTruc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}