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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3bb87f8013ee34197535fdd3d3440d840f95efc86f1c4635b51b3d0464d5e7b' 
  AND token = 'iw6euhA4lF8ekPeZqarD+lA8NWjEjTF0X/HTh2LZPMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}