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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb629d00b0ee0adb457c814a0f5a9cd166d9d2301b5c3fa55a72b813b6f3b792' 
  AND token = 'QIsaHhRGTuB/ymm0YBNuvO5LCYJnr/S3p0D3Gddk1yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}