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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9656974e53edf9fd5a25c41576e3d3211438e1dbf927e81246e4853c1cdc4d88' 
  AND token = '9T0JvCefc1+qdMPfsLelI7PbMDtpQg4lIpHD7uDkS6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}