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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f00412961f5f3fafe9d7ce58b3cec5ebe92148ac41365720271c22f994b5d8' 
  AND token = 'P+Xbz2qS6Ugxj/etkZOunypFxfFt09oQ06boAzypGVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}