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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c187234dba381575ee33106dae0012c339785ccc927af522920bcae681ad24' 
  AND token = 'Fl3BiB5QyDuMZcIUY9H3hUoHK/IyzM99pNcNsSd0MdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}