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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049013112b0a2ba67ba3aefc9729dbd13dfa772fd8713fba2a07a259bb05d3e1' 
  AND token = 'uJ2NWz4Glj2GYgPM2KrMwHXWXCqlatzrPsaf8GY3SWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}