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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7966974cdc2c8d5a945fba053ffd7645ad6518c5a266b06372307b9eed0c0969' 
  AND token = 'dW9ElCpmiNfQg9fQydCkvOd6HyxQs3GAdO0UhzG/vpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}