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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086697175ad3c8886a8d2643a72560fa64180b7aad8c6502b0217235b90a349a' 
  AND token = '1QBX2He4zQXSmVpM+FvukQ1R52TLezQD5jkk7pXViR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}