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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f344110060131593de8c9b7c97bfd9682cbc902f240839b37285354a5d968f' 
  AND token = 'rowFNnWO/4Yi4uybyNYGWP+Dka1OE8MQNaaaQnICbvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}