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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927aed2f3892a52cc2e286708d47cbc8c7975233dfc09b62aaf01c9a8ca4e428' 
  AND token = 'vFFB8s2PvNT0nuOWBVzFpy6X/FZPq6RDrZWmz1+6uA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}